A diagnostic assay based on microRNA expression accurately identifies malignant pleural mesothelioma.

@article{Benjamin2010ADA,
  title={A diagnostic assay based on microRNA expression accurately identifies malignant pleural mesothelioma.},
  author={Hila Benjamin and Danit Lebanony and Shai Rosenwald and Lahav Cohen and Hadas Gibori and Naama Barabash and Karin Ashkenazi and Eran Goren and Eti Meiri and Sara Morgenstern and Marina Perelman and Iris Barshack and Yaron J. Goren and Tina Bocker Edmonston and Ayelet Chajut and Ranit Aharonov and Zvi Bentwich and Nitzan Rosenfeld and Dalia Cohen},
  journal={The Journal of molecular diagnostics : JMD},
  year={2010},
  volume={12 6},
  pages={771-9}
}
The definitive identification of malignant pleural mesothelioma (MPM) has significant clinical implications, yet other malignancies often involve the lung pleura, confounding the diagnosis of MPM. In the absence of accurate markers, MPM can be difficult to distinguish from peripheral lung adenocarcinoma and metastatic epithelial cancers. MicroRNA expression is tissue-specific and highly informative for identifying tumor origin. We identified microRNA biomarkers for the differential diagnosis of… CONTINUE READING
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