A developmental switch in transcription factor isoforms during spermatogenesis controlled by alternative messenger RNA 3'-end formation.

@article{Wang2006ADS,
  title={A developmental switch in transcription factor isoforms during spermatogenesis controlled by alternative messenger RNA 3'-end formation.},
  author={Hang Wang and Becky L Sartini and Clarke F Millette and Daniel L. Kilpatrick},
  journal={Biology of reproduction},
  year={2006},
  volume={75 3},
  pages={318-23}
}
Spermatogeniccells elaborate a highly specialized differentiation program that is mediated in part by germ cell-enriched transcription factors. This includes a novel member of the sterol response element-binding factor family, SREBF2_v1/SREBP2gc. Somatic SREBFs are predominantly synthesized as precursor proteins and are critical regulators of cholesterol… CONTINUE READING

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