A developmental switch in B lymphopoiesis.


B and T lymphocytes are generated from hematopoietic stem cells during both fetal and adult life. A critical unresolved issue is whether the differentiation pathways in lymphopoiesis are the same in fetal and adult animals or whether they differ, similar to the hemoglobin switch in erythropoiesis. We report here that a developmental switch occurs in B… (More)


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@article{Hardy1991ADS, title={A developmental switch in B lymphopoiesis.}, author={R R Hardy and Kayoko Hayakawa}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={1991}, volume={88 24}, pages={11550-4} }