A developmental model for similarities and dissimilarities between schizophrenia and bipolar disorder

@article{Murray2004ADM,
  title={A developmental model for similarities and dissimilarities between schizophrenia and bipolar disorder},
  author={Robin M. Murray and Pak Sham and Jim van Os and Jolanta Zanelli and Colm McDonald},
  journal={Schizophrenia Research},
  year={2004},
  volume={71},
  pages={405-416}
}
Schizophrenia and mania have a number of symptoms and epidemiological characteristics in common, and both respond to dopamine blockade. Family, twin and molecular genetic studies suggest that the reason for these similarities may be that the two conditions share certain susceptibility genes. On the other hand, individuals with schizophrenia have more obvious brain structural and neuropsychological abnormalities than those with bipolar disorder; and pre-schizophrenic children are characterised… CONTINUE READING

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