A detailed predictive model of the mammalian circadian clock.

Abstract

Experimental data on the circadian (approximately 24-h) clock in mammalian cells are vast, diverse, and detailed. Mathematical models are therefore needed to piece these data together and to study overall clock behavior. Previous models have focused on Neurospora or Drosophila or can be converted to a Drosophila model simply by renaming variables. Those… (More)

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