A System Design with Mode-Switching Power Management for Closed-Loop Implantable Biosensor
- Arnold C. Paglinawan, Wen-Yaw Chung, +5 authors Shyh-Liang Lou
- Journal of Medical and Biological Engineering, 31…
The study covered a drug driver system that can be used for continuous glucose monitoring system intended to drive a pump that will administer insulin for the purpose of combating diabetes. The system begins with a microcontroller unit having an analog voltage input that is derived from a calibrated linearity curve relative to that of glucose concentration, the microcontroller algorithm processes the data and determines whether an output of insulin or glucagon is needed. The output of the microcontroller unit is a time variable pulse which is dependent on the glucose concentration reading. Separately, a full custom IC design is conducted for an actual drug driver circuit for the purpose of miniaturization to make the system viable for implantation. The hardware test for the microcontroller unit indicates that the algorithm can be used to properly read glucose concentrations and provide an output accordingly. However, there are delays within the microcontroller which affect the response of the output. For the full custom IC design of the drug driver circuit, it is observed that the parasitic capacitances and resistances affect the propagation delay and power dissipation of the circuit but can still be used in a drug driver system.