A dependent pathway of gene functions leading to chromosome segregation in Saccharomyces cerevisiae

@article{Wood1982ADP,
  title={A dependent pathway of gene functions leading to chromosome segregation in Saccharomyces cerevisiae},
  author={John Stephen Wood and Leland H. Hartwell},
  journal={The Journal of Cell Biology},
  year={1982},
  volume={94},
  pages={718 - 726}
}
Methyl-benzimidazole-2-ylcarbamate (MBC) inhibits the mitotic cell cycle of Saccharomyces cerevisiae at a stage subsequent to DNA synthesis and before the completion of nuclear division (Quinlan, R. A., C. I. Pogson, and K, Gull, 1980, J Cell Sci., 46: 341-352). The step in the cell cycle that is sensitive to MBC inhibition was ordered to reciprocal shift experiments with respect to the step catalyzed by cdc gene products. Execution of the CDC7 step is required for the initiation of DNA… CONTINUE READING
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