A defective HIV-1 vector for gene transfer to human lymphocytes

Abstract

All practical development of HIV-1 vectors for in vivo testing will require high titers of recombinant virus free of helper virus. To date, an HIV-based vector system with an efficiency of gene transfer comparable to that achieved by the Mo-MuLV-based system has not yet been developed. Such development will require a better definition of the optimal… (More)
DOI: 10.1007/BF00231614

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