A defect in platelet aggregation in Bartter's syndrome.

@article{Stoff1980ADI,
  title={A defect in platelet aggregation in Bartter's syndrome.},
  author={Jeffrey S. Stoff and Michael B. Stemerman and Michael L. Steer and Edwin W. Salzman and Rosalind S. Brown},
  journal={The American journal of medicine},
  year={1980},
  volume={68 2},
  pages={
          171-80
        }
}
A defect in both the first and second phase of platelet aggregation was found in four subjects with Bartter's syndrome, although template bleeding times were normal. The platelet abnormality was exacerbated by restriction of dietary sodium and lessened by the administration of inhibitors of prostaglandin synthesis. The aggregation defect was not found in other hypokalemic patients or in sodium-restricted normal control subjects. Platelet rich plasma from the subjects with Bartter's syndrome had… CONTINUE READING

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Biology of Endothelial Cells

  • Developments in Cardiovascular Medicine
  • 1984