A defect in a fatty acyl-CoA synthetase gene, lcf1 + , results in a decrease in viability after entry into the stationary phase in fission yeast

@article{Oshiro2003ADI,
  title={A defect in a fatty acyl-CoA synthetase gene, lcf1 + , results in a decrease in viability after entry into the stationary phase in fission yeast},
  author={Tomoko Oshiro and Hirofumi Aiba and Takeshi Mizuno},
  journal={Molecular Genetics and Genomics},
  year={2003},
  volume={269},
  pages={437-442}
}
An intriguing mutant was isolated in Schizosaccharomyces pombe, which is defective in the maintenance of viability after entry into the stationary phase. In the logarithmic growth phase, the mutant cells grow at the same rate as the parental cells. Upon the onset of the stationary phase, however, the mutant cells lose viability very rapidly. It was found that this phenotype was due to a mutational lesion in the lcf1 + gene, which encodes a long-chain fatty acyl-CoA synthetase. The lcf1Δ mutant… CONTINUE READING
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The Mcs 4 response regulator coordinately controls the stress activated Wak 1Wis 1Sty 1 MAP kinase pathway and fission yeast cell cycle

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