A decade of discovery: CRISPR functions and applications

@article{Barrangou2017ADO,
  title={A decade of discovery: CRISPR functions and applications},
  author={Rodolphe Barrangou and P. Horvath},
  journal={Nature Microbiology},
  year={2017},
  volume={2}
}
This year marks the tenth anniversary of the identification of the biological function of CRISPR–Cas as adaptive immune systems in bacteria. In just a decade, the characterization of CRISPR–Cas systems has established a novel means of adaptive immunity in bacteria and archaea and deepened our understanding of the interplay between prokaryotes and their environment, and CRISPR-based molecular machines have been repurposed to enable a genome editing revolution. Here, we look back on the… 
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