A data-driven approach to optimized medication dosing: a focus on heparin

@article{Ghassemi2014ADA,
  title={A data-driven approach to optimized medication dosing: a focus on heparin},
  author={Mohammad M. Ghassemi and Stefan Richter and Ifeoma M. Eche and Tszyi W. Chen and John I. Danziger and Leo Anthony Celi},
  journal={Intensive Care Medicine},
  year={2014},
  volume={40},
  pages={1332-1339}
}
To demonstrate a novel method that utilizes retrospective data to develop statistically optimal dosing strategies for medications with sensitive therapeutic windows. We illustrate our approach on intravenous unfractionated heparin, a medication which typically considers only patient weight and is frequently misdosed. We identified available clinical… CONTINUE READING