A cytosolic iron chaperone that delivers iron to ferritin.

Abstract

Ferritins are the main iron storage proteins found in animals, plants, and bacteria. The capacity to store iron in ferritin is essential for life in mammals, but the mechanism by which cytosolic iron is delivered to ferritin is unknown. Human ferritins expressed in yeast contain little iron. Human poly (rC)-binding protein 1 (PCBP1) increased the amount of… (More)
DOI: 10.1126/science.1157643

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@article{Shi2008ACI, title={A cytosolic iron chaperone that delivers iron to ferritin.}, author={Haifeng Shi and Krisztina Z Bencze and Timothy L. Stemmler and Caroline C. Philpott}, journal={Science}, year={2008}, volume={320 5880}, pages={1207-10} }