A cytokine-based neuroimmunologic mechanism of cancer-related symptoms.

@article{Lee2004ACN,
  title={A cytokine-based neuroimmunologic mechanism of cancer-related symptoms.},
  author={Bang-Ning Lee and Robert Dantzer and Keith E. Langley and Gary J. Bennett and Patrick M Dougherty and Adrian J. Dunn and Christina Anne Meyers and Antonius A. Miller and Richard S. Payne and James Reuben Reuben and Xin Shelley Wang and Charles S. Cleeland},
  journal={Neuroimmunomodulation},
  year={2004},
  volume={11 5},
  pages={
          279-92
        }
}
While many of the multiple symptoms that cancer patients have are due to the disease, it is increasingly recognized that pain, fatigue, sleep disturbance, cognitive dysfunction and affective symptoms are treatment related, and may lead to treatment delays or premature treatment termination. This symptom burden, a subjective counterpart of tumor burden, causes significant distress. Progress in understanding the mechanisms that underlie these symptoms may lead to new therapies for symptom control… CONTINUE READING
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