A cytogenetic study of human spontaneous abortions using banding techniques

@article{Creasy1976ACS,
  title={A cytogenetic study of human spontaneous abortions using banding techniques},
  author={Michael R. Creasy and John Anthony Crolla and E. D. Alberman},
  journal={Human Genetics},
  year={1976},
  volume={31},
  pages={177-196}
}
The karyotypes of 941 singleton and 42 twin abortuses and 4 cystic placentae were determined. 30.5% of the singletons were chromosomally abnormal; 49.8% of these were trisomic, 23.7% X-monosomics and 17.4% polyploid. 143 trisomies were identified by banding; over a third had an extra chromosome 16, more than 10% and extra 21 or 22 and about 5% an extra 2, 18 or 15. Examples of trisomy 3, 4, 8, 9, 10, 13, 14 and 20 were also encountered. Using the data from two other published studies, the… CONTINUE READING
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