A cyclophilin-related protein involved in the function of natural killer cells.

  title={A cyclophilin-related protein involved in the function of natural killer cells.},
  author={S. K. Anderson and Steven Gallinger and John Roder and Jurgen Frey and Howard A Young and John R. Ortaldo},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={90 2},
Natural killer cells are non-major histocompatibility complex-restricted large granular lymphocytes that can recognize and destroy tumor cells without prior stimulation. A 150-kDa molecule on the surface of human natural killer cells was identified as a component of a putative tumor-recognition complex. We report here the isolation of cDNAs coding for the 150-kDa tumor-recognition molecule from human and mouse cDNA libraries. The amino terminus of the predicted protein contains a large… CONTINUE READING

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