A cyclic-di-GMP receptor required for bacterial exopolysaccharide production

@article{Lee2007ACR,
  title={A cyclic-di-GMP receptor required for bacterial exopolysaccharide production},
  author={Vincent T. Lee and Jody M Matewish and J. L. Kessler and Mamoru Hyodo and Yoshihiro Hayakawa and Stephen Lory},
  journal={Molecular Microbiology},
  year={2007},
  volume={65},
  pages={1474 - 1484}
}
Bis-(3',5')-cyclic-dimeric-guanosine monophosphate (c-di-GMP) has been shown to be a global regulatory molecule that modulates the reciprocal responses of bacteria to activate either virulence pathways or biofilm formation. The mechanism of c-di-GMP signal transduction, including recognition of c-di-GMP and subsequent phenotypic regulation, remain largely uncharacterized. The key components of these regulatory pathways are the various adaptor proteins (c-di-GMP receptors). There is compelling… CONTINUE READING
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