A custom microarray platform for analysis of microRNA gene expression

@article{Thomson2004ACM,
  title={A custom microarray platform for analysis of microRNA gene expression},
  author={John Michael Thomson and Joel Parker and Charles M. Perou and Scott M. Hammond},
  journal={Nature Methods},
  year={2004},
  volume={1},
  pages={47-53}
}
MicroRNAs are short, noncoding RNA transcripts that post-transcriptionally regulate gene expression. Several hundred microRNA genes have been identified in Caenorhabditis elegans, Drosophila, plants and mammals. MicroRNAs have been linked to developmental processes in C. elegans, plants and humans and to cell growth and apoptosis in Drosophila. A major impediment in the study of microRNA function is the lack of quantitative expression profiling methods. To close this technological gap, we have… CONTINUE READING
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