A cryptochrome/photolyase class of enzymes with single-stranded DNA-specific photolyase activity.

  title={A cryptochrome/photolyase class of enzymes with single-stranded DNA-specific photolyase activity.},
  author={Christopher P. Selby and Aziz Sancar},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={103 47},
Photolyases and cryptochrome blue-light photoreceptors are evolutionarily related flavoproteins that perform distinct functions. Photolyases repair UV-damaged DNA in many species from bacteria to plants and animals. Cryptochromes regulate growth and development in plants and the circadian clock in animals. Recently, a new branch of the photolyase/cryptochrome family was identified. Members of this branch exhibited no or trace levels of DNA repair activity in vivo and in vitro and, therefore… CONTINUE READING
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