A crucial role for hydrogen sulfide in oxygen sensing via modulating large conductance calcium-activated potassium channels.

@article{Li2010ACR,
  title={A crucial role for hydrogen sulfide in oxygen sensing via modulating large conductance calcium-activated potassium channels.},
  author={Qian Li and Biying Sun and Xiaofang Wang and Zhu Jin and Yun Zhou and Li Dong and L Jiang and Weifang Rong},
  journal={Antioxidants & redox signaling},
  year={2010},
  volume={12 10},
  pages={1179-89}
}
Hydrogen sulfide (H(2)S) is an important signaling molecule produced from L-cysteine by cystathionine beta-synthetase (CBS) or cystathionine gamma-lyase (CSE). Here we examined the role of H(2)S in the oxygen-sensing function of the carotid body chemoreceptors, where the large conductance Ca(2+)-activated potassium channel (BK(Ca)) plays a key role. In the isolated mouse carotid body/sinus nerve preparations, the H(2)S donor, NaHS, excited the chemoreceptor afferent nerves in a concentration… CONTINUE READING
Highly Influential
This paper has highly influenced 13 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 57 extracted citations

Hydrogen Sulfide as an Oxygen Sensor 2

View 6 Excerpts
Highly Influenced

Carbon monoxide (CO) and hydrogen sulfide (H(2)S) in hypoxic sensing by the carotid body.

Respiratory physiology & neurobiology • 2012
View 10 Excerpts
Highly Influenced

Gaseous messengers in oxygen sensing

Journal of Molecular Medicine • 2012
View 7 Excerpts
Highly Influenced

Oxygen Sensing and Homeostasis.

View 14 Excerpts
Highly Influenced

Sensing hypoxia: physiology, genetics and epigenetics.

The Journal of physiology • 2013
View 5 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…