A crossover randomised controlled trial of oral mandibular advancement devices for obstructive sleep apnoea-hypopnoea (TOMADO).

@article{Quinnell2014ACR,
  title={A crossover randomised controlled trial of oral mandibular advancement devices for obstructive sleep apnoea-hypopnoea (TOMADO).},
  author={Timothy George Quinnell and Maxine Sarah Bennett and Jake Jordan and Abigail L. Clutterbuck-James and Michael Gordon Davies and Ian E. Smith and Nicholas Stephen Oscroft and Marcus Anthony Pittman and Malcolm Gregor Cameron and Rebecca Chadwick and Mary J. Morrell and Matthew J. Glover and Julia Fox-Rushby and Linda D. Sharples},
  journal={Thorax},
  year={2014},
  volume={69 10},
  pages={
          938-45
        }
}
RATIONALE Mandibular advancement devices (MADs) are used to treat obstructive sleep apnoea-hypopnoea syndrome (OSAHS) but evidence is lacking regarding their clinical and cost-effectiveness in less severe disease. OBJECTIVES To compare clinical- and cost-effectiveness of a range of MADs against no treatment in mild to moderate OSAHS. MEASUREMENTS AND METHODS This open-label, randomised, controlled, crossover trial was undertaken at a UK sleep centre. Adults with Apnoea-Hypopnoea Index (AHI… CONTINUE READING
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