A cross-sectional MRI study of brain regional atrophy and clinical characteristics of temporal lobe epilepsy with hippocampal sclerosis.

@article{Alhusaini2012ACM,
  title={A cross-sectional MRI study of brain regional atrophy and clinical characteristics of temporal lobe epilepsy with hippocampal sclerosis.},
  author={Saud Alhusaini and C P Doherty and Cathy Scanlon and Lisa Ronan and Sinead Maguire and G{\'a}bor Borgulya and Paul Brennan and Norman Delanty and Mary Fitzsimons and Gianpiero L Cavalleri},
  journal={Epilepsy research},
  year={2012},
  volume={99 1-2},
  pages={156-66}
}
PURPOSE Applying a cross-sectional design, we set out to further characterize the significance of extrahippocampal brain atrophy in a large sample of 'sporadic' mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE+HS). By evaluating the influence of epilepsy chronicity on structural atrophy, this work represents an important step towards the characterization of MRI-based volumetric measurements as genetic endophenotypes for this condition. METHODS Using an automated brain… CONTINUE READING