A critical role of vascular endothelial growth factor D in zebrafish embryonic vasculogenesis and angiogenesis.

@article{Song2007ACR,
  title={A critical role of vascular endothelial growth factor D in zebrafish embryonic vasculogenesis and angiogenesis.},
  author={Min Song and Hanshuo Yang and Shaohua Yao and Fanxin Ma and Zhijun Li and Yaqi Deng and Hongxin Deng and Qin Zhou and Shuo Lin and Yu-Quan Wei},
  journal={Biochemical and biophysical research communications},
  year={2007},
  volume={357 4},
  pages={924-30}
}
The VEGF family comprises seven members that are designated VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-E, placental growth factor (PlGF), and VEGF-F. Of these factors, VEGF-D plays important roles for angiogenesis and lymphangiogenesis, and could promote tumor growth and lymphatic metastasis. In this study, we identified a zebrafish VEGF-D homolog that encodes a 272 amino acid protein including a PDGF (platelet-derived growth factor) domain characteristic to VEGF family. Expression profile… CONTINUE READING

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Lymphangiogenesis: in vitro and in vivo models.

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