A critical role for immature muscle precursors in myositis

  title={A critical role for immature muscle precursors in myositis},
  author={Anne Tournadre and Pierre Miossec},
  journal={Nature Reviews Rheumatology},
The innate and adaptive immune responses contribute to the development of inflammatory myopathies; the innate immune system does so through activation of the type I interferon and Toll-like receptor pathways. Dendritic cells have a pivotal role in the development of both adaptive and innate immune responses. Equipped with a range of pattern-recognition receptors, dendritic cells link innate and adaptive immunity. This Perspectives article discusses novel concepts in myositis, focusing on… CONTINUE READING
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Publications referenced by this paper.

Effects of immunosuppressive treatment on interleukin-15 and interleukin-15 receptor α expression in muscle tissue of patients with polymyositis and dermatomyositis

  • M Zong
  • Ann. Rheum. Dis
  • 2012

Type I interferon and Toll-like receptor expression characterizes inflammatory myopathies

  • Cappelletti, F C.B.
  • Neurology 76,
  • 2011

interaction with dendritic cells and possible link with response to high-dose immunoglobulins

  • Tournadre, A. et al. TH1, TH17 balance in inflammatory myopathies
  • Cytokine 46, 297–301
  • 2009