A critical re-appraisal of BRCA1 methylation studies in ovarian cancer.

@article{Senturk2010ACR,
  title={A critical re-appraisal of BRCA1 methylation studies in ovarian cancer.},
  author={Emir Senturk and Samantha Cohen and Peter R. Dottino and John A. Martignetti},
  journal={Gynecologic oncology},
  year={2010},
  volume={119 2},
  pages={376-83}
}
A central challenge facing gynecologic oncology is achieving personalized care in ovarian cancer treatment. The current ovarian cancer classification scheme distinguishes tumors based on histopathologic subtype, grade, and surgical stage. Recent molecular investigations have highlighted distinguishing genetic features of certain tumors within a given category, and given the rapid pace of technologic advancement combined with plummeting costs for complete genomic sequencing this classification… CONTINUE READING
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Principles and Practice of Gynecologic Oncology

  • GF Fleming, BM Ronnett
  • 2009
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