A critical period requiring Rho proteins for cell cycle progression uncovered by reversible protein transduction in endothelial cells.

@article{Hirano2004ACP,
  title={A critical period requiring Rho proteins for cell cycle progression uncovered by reversible protein transduction in endothelial cells.},
  author={Katsuya Hirano and Mayumi Hirano and Junji Nishimura and Hideo Kanaide},
  journal={FEBS letters},
  year={2004},
  volume={570 1-3},
  pages={149-54}
}
The time-specific requirement of Rho proteins for the S phase progression of vascular endothelial cells was determined by reversibly introducing inhibitor proteins with a cell-penetrating peptide. We found evidence of the reversibility of protein transduction. The removal of extracellular protein caused the transduced protein to decay in a manner sensitive… CONTINUE READING