A critical look at phenytoin use for early post-traumatic seizure prophylaxis.

  title={A critical look at phenytoin use for early post-traumatic seizure prophylaxis.},
  author={Sierra Debenham and Behzad Sabit and Rajeet Singh Saluja and Julie Lamoureux and Paul Bajsarowicz and Mohammad Hassan Maleki and Judith Marcoux},
  journal={The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques},
  volume={38 6},
BACKGROUND The American Academy of Neurology recommended using phenytoin or carbamazepine to prevent early post-traumatic seizures (PTS) in severe traumatic brain injuries (TBI). In this study, we examined the effects of using phenytoin prophylaxis on mild, moderate, and severe TBIs. There have been no studies looking at compliance rate and side effects of systematic use of phenytoin at a large population scale. The goal of this study is to determine 1) the proportion of TBI patients receiving… CONTINUE READING
8 Citations
24 References
Similar Papers


Publications citing this paper.
Showing 1-8 of 8 extracted citations


Publications referenced by this paper.
Showing 1-10 of 24 references

The role of prophylactic anticonvulsants in moderate to severe head injury

  • SD Darrah, J Chuang, LM Mohler
  • Int J Emerg Med
  • 2010

Role of antiseizure prophylaxis following head injury

  • MJ Jacka, D Zygun
  • J Neurotraum
  • 2007

Prophylaxis of the epilepsies : should anti - epileptic drugs be used for preventing seizures after acute brain injury ?

  • AA Khan, A Banerjee
  • Acta Neurol Belg
  • 2005

Similar Papers

Loading similar papers…