A critical evaluation of loss of heterozygosity detected in tumor tissues, blood serum and bone marrow plasma from patients with breast cancer

@article{Schwarzenbach2007ACE,
  title={A critical evaluation of loss of heterozygosity detected in tumor tissues, blood serum and bone marrow plasma from patients with breast cancer},
  author={Heidi Schwarzenbach and Volkmar Mueller and Cord Beeger and Miriam Gottberg and Nicole Stahmann and Klaus Pantel},
  journal={Breast cancer research : BCR},
  year={2007},
  volume={9},
  pages={R66 - R66}
}
The aim of the study was to perform a comparative analysis of LOH (loss of heterozygosity) in primary tumors as well as peripheral blood and bone marrow (BM) of patients with breast cancer (BCa). Performing PCR-based fluorescence microsatellite analysis and using a panel of seven polymorphic microsatellite markers, we compared the profiles of LOH in primary tumors, peripheral blood and BM plasma from patients with primary BCa (n = 40, stage M0) as well as tumor tissues and blood serum from… CONTINUE READING

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Comparison of genetic alterations detected in circulating Microsatellite-DNA in blood plasma samples of patients with prostate cancer and benign prostatic hyperplasia

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  • Ann NY Acad Sci
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