# A critical assessment of force field accuracy against NMR data for cyclic peptides containing β-amino acids.

@article{Paissoni2018ACA,
title={A critical assessment of force field accuracy against NMR data for cyclic peptides containing $\beta$-amino acids.},
author={C. Paissoni and F. Nardelli and S. Zanella and F. Curnis and L. Belvisi and G. Musco and M. Ghitti},
journal={Physical chemistry chemical physics : PCCP},
year={2018},
volume={20 23},
pages={
15807-15816
}
}
• C. Paissoni, +4 authors M. Ghitti
• Published 2018
• Physics, Medicine
• Physical chemistry chemical physics : PCCP
Hybrid cyclic α/β-peptides, in which one or more β-amino acids are incorporated into the backbone, are gaining increasing interest as potential therapeutics, thanks to their ability to achieve enhanced binding affinities for a biological target through pre-organization in solution. The in silico prediction of their three dimensional structure through strategies such as MD simulations would substantially advance the rational design process. However, whether the molecular mechanics force fields… Expand
2 Citations

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