A critical appraisal of "chronic Lyme disease".

  title={A critical appraisal of "chronic Lyme disease".},
  author={H. Feder and Barbara J. B. Johnson and S. O'connell and E. Shapiro and A. Steere and G. Wormser and W. Agger and H. Artsob and P. Auwaerter and J. Dumler and J. S. Bakken and L. Bockenstedt and J. Green and R. Dattwyler and J. Munoz and R. Nadelman and I. Schwartz and T. Draper and E. Mcsweegan and J. Halperin and M. Klempner and P. Krause and P. Mead and M. Morshed and R. Porwancher and J. D. Radolf and R. Smith and S. Sood and A. Weinstein and S. Wong and L. Zemel},
  journal={The New England journal of medicine},
  volume={357 14},
  • H. Feder, Barbara J. B. Johnson, +28 authors L. Zemel
  • Published 2007
  • Medicine
  • The New England journal of medicine
  • “Chronic Lyme disease” is often used to explain persistent pain, fatigue, and neurocognitive symptoms in patients without any evidence of previous acute Lyme disease. Once this diagnosis is given, prolonged treatment with multiple antimicrobial agents may follow. This review examines the scientific evidence for chronic borrelia infection and explains the approach to clinical evaluation and management in patients with a diagnosis of chronic Lyme disease. 
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