A cortico-cortical mechanism mediating object-driven grasp in humans.

  title={A cortico-cortical mechanism mediating object-driven grasp in humans.},
  author={Luigi Cattaneo and Martin H Voss and Thomas Brochier and Gita Prabhu and Daniel M. Wolpert and R. N. Lemon},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={102 3},
Humans and other primates demonstrate an exquisite ability to precisely shape their hand when reaching out to grasp an object. Here we used a recently developed transcranial magnetic stimulation paradigm to examine how information about an object's geometric properties is transformed into specific motor programs. Pairs of transcranial magnetic stimulation pulses were delivered at precise intervals to detect changes in the excitability of cortico-cortical inputs to motor cortex when subjects… CONTINUE READING


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