A correlation between function and selected measures of T cell avidity in influenza virus-specific CD8+ T cell responses.

Abstract

Activation of mature CD8+ T cells requires recognition, via the T cell receptor (TCR), of peptide + MHC (pMHC) complexes with an avidity that exceeds a designated threshold. Multiple indicators of T cell avidity have been described that provide unique information on the characteristics of T cell interactions. However, these indicators are routinely used in… (More)

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Cite this paper

@article{Gruta2006ACB, title={A correlation between function and selected measures of T cell avidity in influenza virus-specific CD8+ T cell responses.}, author={Nicole L La Gruta and Peter C. Doherty and Stephen J. Turner}, journal={European journal of immunology}, year={2006}, volume={36 11}, pages={2951-9} }