A core paired-type and POU homeodomain-containing transcription factor program drives retinal bipolar cell gene expression.

@article{Kim2008ACP,
  title={A core paired-type and POU homeodomain-containing transcription factor program drives retinal bipolar cell gene expression.},
  author={Douglas S Kim and Takahiko Matsuda and Constance L. Cepko},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2008},
  volume={28 31},
  pages={
          7748-64
        }
}
The diversity of cell types found within the vertebrate CNS arises in part from action of complex transcriptional programs. In the retina, the programs driving diversification of various cell types have not been completely elucidated. To investigate gene regulatory networks that underlie formation and function of one retinal circuit component, the bipolar cell, transcriptional regulation of three bipolar cell-enriched genes was analyzed. Using in vivo retinal DNA transfection and reporter gene… CONTINUE READING

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