A convenient method for producing the bleomycin-induced mouse model of scleroderma by weekly injections using a methylcellulose gel

Abstract

Systemic sclerosis (SSc) is a connective tissue disease characterized by vasculopathy, excessive accumulation of extracellular matrix, and fibrosis of the skin and internal organs. An animal model of SSc, the bleomycin-induced mouse model, has been established and used extensively to investigate the pathogenesis of SSc and to seek novel therapeutic agents… (More)
DOI: 10.1007/s00296-011-1884-0

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@article{Jun2011ACM, title={A convenient method for producing the bleomycin-induced mouse model of scleroderma by weekly injections using a methylcellulose gel}, author={J. H. Jun and Jang Kyoung Kim and Young-In Na and Se Min Jang and Seung Sam Paik and Yong-Hee Kim}, journal={Rheumatology International}, year={2011}, volume={32}, pages={1443-1447} }