A convenient LC-MS method for assessment of glucose kinetics in vivo with D-[13C6]glucose as a tracer.

Abstract

BACKGROUND The isotope-labeled intravenous glucose tolerance test (IVGTT) combined with computer modeling is widely used to derive parameters related to glucose metabolism in vivo. Most of these methods involve use of either (2)H(2)-labeled or (13)C(1)-labeled D-glucose as a tracer with GC-MS to measure the isotope enrichment. These methods are challenging… (More)
DOI: 10.1373/clinchem.2008.113654

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@article{Zhang2009ACL, title={A convenient LC-MS method for assessment of glucose kinetics in vivo with D-[13C6]glucose as a tracer.}, author={Haoyue H Zhang and Robert Stevens and Sarah P. Young and Richard S. Surwit and Anastasia Georgiades and Raymond C. Boston and David S. Millington}, journal={Clinical chemistry}, year={2009}, volume={55 3}, pages={527-32} }