A controlled trial of topical propylthiouracil in the treatment of patients with psoriasis.

@article{Elias1994ACT,
  title={A controlled trial of topical propylthiouracil in the treatment of patients with psoriasis.},
  author={Alan N Elias and Kirsten Dangaran and Ronald J. Barr and Maheswaran Rohan and M M Goodman},
  journal={Journal of the American Academy of Dermatology},
  year={1994},
  volume={31 3 Pt 1},
  pages={455-8}
}
BACKGROUND Propylthiouracil (PTU, 6-n-propyl 2-thiouracil) is an antithyroid thioureylene, which, in addition to its ability to decrease thyroid hormone synthesis, also has immune modulatory and free radical scavenging abilities. We have previously shown that oral PTU and another antithyroid thioureylene are effective in the treatment of plaque psoriasis… CONTINUE READING