A controlled trial of the tolerance of amphotericin B infused in dextrose or in Intralipid in patients with haematological malignancies.

@article{Caillot1994ACT,
  title={A controlled trial of the tolerance of amphotericin B infused in dextrose or in Intralipid in patients with haematological malignancies.},
  author={D. Caillot and G. Reny and E. Solary and O. Casasnovas and P. Chavanet and B. Bonnotte and L. Perello and M. Dumas and F. Entezam and H. Guy},
  journal={The Journal of antimicrobial chemotherapy},
  year={1994},
  volume={33 3},
  pages={
          603-13
        }
}
Patients with haematological malignancies requiring an antifungal therapy were randomly assigned to receive amphotericin B diluted in either 5% dextrose or in fat emulsion (Intralipid). Twenty-one patients were included in each group. Mean duration of amphotericin B therapy was 8.4 days in the dextrose group and 12.8 days in the Intralipid group. Amphotericin B infusion induced chills in 16 of 21 patients in the dextrose group and in 5 of 21 in the Intralipid group (P = 0.0008). Serum… Expand
Amphotericin B in a lipid emulsion for the treatment of cryptococcal meningitis in AIDS patients.
Toxicity and efficacy of conventional amphotericin B deoxycholate versus escalating doses of amphotericin B deoxycholate---fat emulsion in HIV-infected patients with oral candidosis.
  • P. Chavanet, Claudine Clement, +5 authors H. Portier
  • Medicine
  • Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
  • 1997
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