A controlled trial of intermittent oral acetylcysteine in the long-term treatment of chronic bronchitis

@article{Grassi1976ACT,
  title={A controlled trial of intermittent oral acetylcysteine in the long-term treatment of chronic bronchitis},
  author={Carmine Grassi and Giancarlo Morandini},
  journal={European Journal of Clinical Pharmacology},
  year={1976},
  volume={9},
  pages={393-396}
}
In 69 out-patients with chronic bronchitis in 6 centres the effects of acetylcysteine 600 mg daily, 3 days a week for 6 months, and a placebo have been compared in a double-blind controlled trial. Thirty-five patients were treated with the mucolytic and 34 with the dummy preparation. In the former the clinical course of the chronic bronchitis improved to a greater extent and a significantly lower number of exacerbations was observed. The advantages of long-term oral treatment with the mucolytic… CONTINUE READING

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