A controlled trial of human lymphoblastoid interferon in chronic hepatitis B in Italy.

@article{Saracco1989ACT,
  title={A controlled trial of human lymphoblastoid interferon in chronic hepatitis B in Italy.},
  author={Giorgio Saracco and Giuseppe Mazzella and Floriano Rosina and Claudio Cancellieri and V Lattore and Enzo Raise and G. Rocca and Laura M Giorda and Giorgio Verme and Giovanni Battista Gasbarrini},
  journal={Hepatology},
  year={1989},
  volume={10 3},
  pages={336-41}
}
Sixty-four heterosexual Italian carriers of HBsAg with chronic HBeAg and hepatitis B virus DNA-positive hepatitis were assigned randomly either to receive human lymphoblastoid interferon (injections of 5 million units per m2 three times per week for 6 months) or to serve as untreated controls. After 18 months of follow-up evaluation, 26 of the 33 treated patients (79%) had cleared hepatitis B virus DNA, 23 (70%) had lost HBeAg and 20 (61%) had seroconverted to anti-HBe. Fifteen of the 31… CONTINUE READING

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Chronic hepatitis B.

The New England journal of medicine • 2002

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