A continuous multicolumn countercurrent solvent gradient purification (MCSGP) process

@article{Aumann2007ACM,
  title={A continuous multicolumn countercurrent solvent gradient purification (MCSGP) process},
  author={L. Aumann and M. Morbidelli},
  journal={Biotechnology and Bioengineering},
  year={2007},
  volume={98}
}
Biomolecules are often purified via solvent gradient batch chromatography. Typically suitable smooth linear solvent gradients are applied to obtain the separation between the desired component and hundreds of impurities. The desired product is usually intermediate between weakly and strongly adsorbing impurities, and therefore a central cut is required to get the desired pure product. The stationary phases used for preparative and industrial separations have a low efficiency due to strong axial… Expand
multifraction separation in countercurrent chromatography (MCSGP)
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References

SHOWING 1-8 OF 8 REFERENCES
Solvent gradient operation of simulated moving beds. 2. Langmuir isotherms.