A conserved signaling network monitors delivery of sphingolipids to the plasma membrane in budding yeast

@inproceedings{Clarke2017ACS,
  title={A conserved signaling network monitors delivery of sphingolipids to the plasma membrane in budding yeast},
  author={Jesse Clarke and Noah Dephoure and Ira Horecka and Steven P Gygi and Douglas R. Kellogg},
  booktitle={Molecular biology of the cell},
  year={2017}
}
In budding yeast, cell cycle progression and ribosome biogenesis are dependent on plasma membrane growth, which ensures that events of cell growth are coordinated with each other and with the cell cycle. However, the signals that link the cell cycle and ribosome biogenesis to membrane growth are poorly understood. Here we used proteome-wide mass spectrometry to systematically discover signals associated with membrane growth. The results suggest that membrane trafficking events required for… CONTINUE READING
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