A conserved motif in Crumbs is required for E-cadherin localisation and zonula adherens formation in Drosophila

@article{Klebes2000ACM,
  title={A conserved motif in Crumbs is required for E-cadherin localisation and zonula adherens formation in Drosophila},
  author={Ansgar Klebes and Elisabeth Knust},
  journal={Current Biology},
  year={2000},
  volume={10},
  pages={76-85}
}
BACKGROUND Specialised cell junctions in epithelia serve as cell-cell adhesion sites and thus contribute to the maintenance of tissue integrity. The Drosophila gene crumbs encodes a transmembrane protein that is required for the biogenesis of the zonula adherens, a belt-like structure encircling the apex of epithelial cells. As previously shown, expression of just the short membrane-bound cytoplasmic domain is sufficient to rescue major defects associated with the loss of crumbs function… CONTINUE READING
Highly Influential
This paper has highly influenced 16 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 109 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 46 references

Similar Papers

Loading similar papers…