A conserved matrix epitope based DNA vaccine protects mice against influenza A virus challenge.


DNA vaccination represents a unique strategy to overcome the limitations of immunization with conventional vaccines which is restricted by the high variability of influenza viruses. We evaluated the protective efficacy of a plasmid DNA (pDNA), encoding an evolutionarily conserved epitope of viral matrix protein, against the influenza A virus infection. It… (More)
DOI: 10.1016/j.antiviral.2011.10.021