A conserved domain targets exported PHISTb family proteins to the periphery of Plasmodium infected erythrocytes

@inproceedings{Tarr2014ACD,
  title={A conserved domain targets exported PHISTb family proteins to the periphery of Plasmodium infected erythrocytes},
  author={Sarah J. Tarr and Robert W Moon and Iris Hardege and Andrew R. Osborne},
  booktitle={Molecular and biochemical parasitology},
  year={2014}
}
During blood-stage infection, malaria parasites export numerous proteins to the host erythrocyte. The Poly-Helical Interspersed Sub-Telomeric (PHIST) proteins are an exported family that share a common 'PRESAN' domain, and include numerous members in Plasmodium falciparum, Plasmodium vivax and Plasmodium knowlesi. In P. falciparum, PHIST proteins have been implicated in protein trafficking and intercellular communication. A number of PHIST proteins are essential for parasite survival. Here, we… CONTINUE READING
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