A conserved anti-repressor controls horizontal gene transfer by proteolysis.

@article{Bose2008ACA,
  title={A conserved anti-repressor controls horizontal gene transfer by proteolysis.},
  author={Baundauna Bose and Jennifer M Auchtung and Catherine A. A. Lee and Alan D Grossman},
  journal={Molecular microbiology},
  year={2008},
  volume={70 3},
  pages={
          570-82
        }
}
The mobile genetic element ICEBs1 is an integrative and conjugative element (a conjugative transposon) found in the Bacillus subtilis chromosome. The SOS response and the RapI-PhrI sensory system activate ICEBs1 gene expression, excision and transfer by inactivating the ICEBs1 repressor protein ImmR. Although ImmR is similar to many characterized phage repressors, we found that, unlike these repressors, inactivation of ImmR requires an ICEBs1-encoded anti-repressor ImmA (YdcM). ImmA was needed… CONTINUE READING

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