A consensus RNA signal that directs germ layer determinants to the vegetal cortex of Xenopus oocytes.

@article{Bubunenko2002ACR,
  title={A consensus RNA signal that directs germ layer determinants to the vegetal cortex of Xenopus oocytes.},
  author={Mikhail Bubunenko and Tracy L. Kress and Uma Devi Vempati and Kimberly L. Mowry and Mary Lou King},
  journal={Developmental biology},
  year={2002},
  volume={248 1},
  pages={82-92}
}
RNA localization is an important mechanism for generating cellular diversity and polarity in the early embryo. In Xenopus, the correct localization of the RNA encoding the T-box transcription factor VegT is essential for the correct spatial organization and identity of endoderm and mesoderm. Although localization signals in the 3' UTR have been identified for many localized RNAs, insight into what constitutes an RNA localization signal remains elusive. To investigate possible common features… CONTINUE READING