A conjugative plasmid carrying the carbapenem resistance gene blaOXA-23 in AbaR4 in an extensively resistant GC1 Acinetobacter baumannii isolate.

@article{Hamidian2014ACP,
  title={A conjugative plasmid carrying the carbapenem resistance gene blaOXA-23 in AbaR4 in an extensively resistant GC1 Acinetobacter baumannii isolate.},
  author={Mohammad Hamidian and Johanna J. Kenyon and Kathryn E Holt and Derek John Juan Pickard and Ruth M Hall},
  journal={The Journal of antimicrobial chemotherapy},
  year={2014},
  volume={69 10},
  pages={2625-8}
}
OBJECTIVES To locate the acquired bla(OXA-23) carbapenem resistance gene in an Australian A. baumannii global clone 1 (GC1) isolate. METHODS The genome of the extensively antibiotic-resistant GC1 isolate A85 harbouring bla(OXA-23) in Tn2006 was sequenced using Illumina HiSeq, and the reads were used to generate a de novo assembly. PCR was used to assemble relevant contigs. Sequences were compared with ones in GenBank. Conjugation experiments were conducted. RESULTS The sporadic GC1 isolate… CONTINUE READING
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