A conditioning lesion enhances sympathetic neurite outgrowth.

  title={A conditioning lesion enhances sympathetic neurite outgrowth.},
  author={Sarah E. Shoemaker and Hilary Hyatt Sachs and Stacey A Vaccariello and Richard E Zigmond},
  journal={Experimental neurology},
  volume={194 2},
Axonal regeneration can be influenced by a conditioning lesion (an axonal injury made prior to a second test lesion). Previously, sympathetic neurons in vivo were shown to respond to a conditioning lesion with decreased neurite outgrowth, in contrast to the enhanced outgrowth observed in all other peripheral neurons examined. The present experiments tested the effects of a conditioning lesion on neurite outgrowth in vitro from the superior cervical ganglion (SCG) and the impact of several… CONTINUE READING


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