A conditionally immortalized human podocyte cell line demonstrating nephrin and podocin expression.

@article{Saleem2002ACI,
  title={A conditionally immortalized human podocyte cell line demonstrating nephrin and podocin expression.},
  author={Moin Saleem and M J O'hare and Jochen Reiser and Richard J. M. Coward and Carol D. Inward and Timothy W. Farren and Chang Ying Xing and Lan Ni and Peter William Mathieson and Peter H. Mundel},
  journal={Journal of the American Society of Nephrology : JASN},
  year={2002},
  volume={13 3},
  pages={630-8}
}
Recent molecular insights have established the podocyte as a key component of the glomerular filtration barrier, and hence an important common pathway in proteinuric diseases. A conditionally immortalized human podocyte cell line has been developed by transfection with the temperature-sensitive SV40-T gene. These cells proliferate at the "permissive" temperature (33 degrees C). After transfer to the "nonpermissive" temperature (37 degrees C), they entered growth arrest and expressed markers of… CONTINUE READING
Highly Influential
This paper has highly influenced 22 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

From This Paper

Topics from this paper.
367 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 367 extracted citations

Similar Papers

Loading similar papers…