A conceptual framework: the early and late phases of skeletal muscle dysfunction in the acute respiratory distress syndrome

@inproceedings{Files2015ACF,
  title={A conceptual framework: the early and late phases of skeletal muscle dysfunction in the acute respiratory distress syndrome},
  author={D Clark Files and Michael A. Sanchez and Peter E. Morris},
  booktitle={Critical care},
  year={2015}
}
Patients with acute respiratory distress syndrome (ARDS) often develop severe diaphragmatic and limb skeletal muscle dysfunction. Impaired muscle function in ARDS is associated with increased mortality, increased duration of mechanical ventilation, and functional disability in survivors. In this review, we propose that muscle dysfunction in ARDS can be categorized into an early and a late phase. These early and late phases are based on the timing in relationship to lung injury and the… CONTINUE READING
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